SLU study aids to find cure for Alzheimer’s disease

This is an archived article and the information in the article may be outdated. Please look at the time stamp on the story to see when it was last updated.

(KTVI) - Finding a cure for Alzheimer's disease is the quest. Dr. Maurice Redden, Assistant Professor of Geriatric Psychiatry at SLU Hospital,  joins us with news of a drug and study.

MERK developed a drug MK-8931 intended to break down plaque.

BACE is A key enzyme in the production of amyloid β peptide.  Evidence suggests that inhibiting BACE decreases the production of amyloid β peptide and may therefore reduce amyloid plaque formation and modify Alzheimer`s disease progression.

MK-8931 is a BACE inhibitor.

Saint Louis University will enroll participants with mild to moderate Alzheimer`s disease in a new research study examining the efficacy and safety of an investigational drug known as MK-8931 in treating the illness.

The study is a randomized, placebo-controlled, double-blind Phase II/III clinical trial designed to determine how safe and effective MK-8931 is at two oral doses, 12 mg and 40 mg. Patients with mild to moderate Alzheimer`s disease will receive the drug or a placebo.

If you know of someone who is able to run a screen with the study number, call (314) 977-4900.

Notice: you are using an outdated browser. Microsoft does not recommend using IE as your default browser. Some features on this website, like video and images, might not work properly. For the best experience, please upgrade your browser.